T-cell lineage fate: Instructed by receptor signals?
نویسنده
چکیده
Mechanisms of lineage choice represent a challenging problem in developmental biology. Recent studies have shown that different T-cell receptor signals can affect CD4 or CD8 lineage choice. Thus, all the ingredients for instructive mechanisms of lineage fate are in place but other mechanisms cannot be completely ruled out.
منابع مشابه
T cell receptor–instructed αβ versus γδ lineage commitment revealed by single-cell analysis
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عنوان ژورنال:
- Current Biology
دوره 10 شماره
صفحات -
تاریخ انتشار 2000